Revelation 8:10 Then the third angel sounded: And a great star fell from heaven, burning like a torch, and it fell on a third of the rivers and on the springs of water. 11 The name of the star is Wormwood. A third of the waters became wormwood, and many men died from the water, because it was made bitter.
A third of all the fresh water supply is turned bitter or toxic. Many will continue to drink from these sources due to necessity, only to their peril. Now remember, God never appointed man to His wrath. All these upon earth have chosen to reject God still. Satan is a cruel slavemaster who uses deceptions to enslave. At any point currently, men can and should fall to their knees, repent, & confess their sin unto God. Thank You LORD for the simple gift of humility to accept You now.